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    WHO grants first mpox vaccine approval to ramp up response to disease in Africa, ET HealthWorld


    Geneva: The World Health Organisation said Friday it has granted its first authorisation for use of a vaccine against mpox in adults, calling it an important step toward fighting the disease in Africa.

    The approval of the vaccine by Bavarian Nordic A/S means that donors like vaccines alliance Gavi and UNICEF can buy it. But supplies are limited because there’s only a single manufacturer.

    “This first (authorisation) of a vaccine against mpox is an important step in our fight against the disease, both in the context of the current outbreaks in Africa, and in future,” said WHO Director-General Tedros Adhanom Ghebreyesus.

    The U.N. health agency chief called for “urgent” scale-up of procurement, donations and rollout to get the vaccine where it is needed most, along with other response measures.

    Under the WHO authorisation, the vaccine can be administered in people aged 18 or above in a two-dose regimen. The approval says that while the vaccine is not currently licensed for those under 18 years old, it may be used in infants, children and adolescents “in outbreak settings where the benefits of vaccination outweigh the potential risks.”

    The mpox vaccine made by Bavarian Nordic was previously authorised by numerous rich countries across Europe and North America during the global mpox outbreak in 2022. Millions of doses given to adults showed the vaccine helped slow the virus’ spread, but there is limited evidence of how it works in children.

    Officials at the Africa Center for Disease Control and Prevention said last month that nearly 70 per cent of cases in Congo – the country hardest hit by mpox – are in children younger than 15, who also accounted for 85 per cent of deaths.

    Overall, WHO said over 120 countries have confirmed more than 103,000 cases of mpox since the outbreak began two years ago. Its latest tally, as of Sunday, showed that 723 people in more than a dozen countries in Africa have died of the disease.

    African experts have estimated they might need about 10 million vaccines to stop the ongoing outbreaks on the continent. As of last week, Congo, the most-affected country, had received only about 250,000 doses.

    On Thursday, the Africa CDC said 107 new deaths and 3,160 new cases had been recorded in the past week, just a week after it and WHO launched a continental response plan.

    Mpox belongs to the same family of viruses as smallpox but causes milder symptoms like fever, chills and body aches. People with more serious cases can develop lesions on the face, hands, chest and genitals.

    • Published On Sep 13, 2024 at 06:13 PM IST

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